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Cindy Crawford Unveils Iconic Partnership with Upneeq®

Campaign puts focus on connection, presence and the power of showing up fully

Roastbrief by Roastbrief
May 28, 2026
in Agency, Brands, Campaign
Reading Time: 4 mins read
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Cindy Crawford Unveils Iconic Partnership with Upneeq®
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BRIDGEWATER, N.J., May 27, 2026 /PRNewswire/ — RVL Pharmaceuticals today announced that Cindy Crawford, supermodel, entrepreneur, and cultural icon whose confidence and influence have spanned decades, is partnering with Upneeq® (oxymetazoline hydrochloride), a once-daily prescription eye drop for adults with low-lying eyelids (acquired blepharoptosis).

As eyes continue to be a key area of focus in facial aesthetics, the brand aims to educate on the power of Upneeq, the first and only FDA-approved non-surgical eyelid lift that helps eyes appear more open and awake-looking in minutes and lasts up to 8 hours. A long time Upneeq user herself, Crawford brings a personal connection to the partnership through her own experience with the product. She shares how Upneeq fits into her routine, which is rooted in her approach to simple, effective steps that help her feel like herself and show up fully.

“Connection has always been about presence and confidence for me, and so much of that is communicated through the eyes,” said Cindy Crawford. “Upneeq allows me to continue to show up fully, just as I have throughout my career.”

The campaign weaves in subtle references to Cindy’s iconic career, creating a sense of recognition and nostalgia across generations.

“This partnership represents a powerful convergence, bringing together a true cultural icon like Cindy Crawford with Upneeq, a category-defining innovator in eye care,” said Lori Deo, Chief Executive Officer.  “This campaign celebrates presence and connection in everyday moments, and Cindy has built a legacy of meaningful connection across generations. We’re thrilled to bring this defining partnership to life.”

The multichannel campaign will roll out across digital and social platforms, featuring creators, makeup artists, and women of all ages sharing their own perspectives on connection, confidence, and showing up fully. The campaign also extends to healthcare professionals designed to support patient awareness and conversations around eye aesthetics, further expanding the campaign’s reach across both consumer and provider audiences.

Upneeq is available by prescription. For more information and to see the campaign, visit Upneeq.com.

CREDITS:
Brand: Upneeq
 
Agency: /promptChief Creative Officer: Dan West
Creative Director: Laura Touysinhthiphonexay
Associate Creative Director, Copy: Sydney Olstad
Associate Creative Director, Art: Melissa Sohmer
Head of Production: Taylor SchomannManaging Director, Client Experience: Jamie Jacobson 
Audience Experience: Jeremy Simon 
Managing Director, Talent Partnership: Alyssa Ciambriello
Senior Vice President, Client Experience: Kristina Ellis 
Account Director, Client Experience: Laura Bastings 
Account Supervisor: Naomi Pittinsky 
Senior Vice President, Digital: Cass Hallacker-Covaleski 
Director, Growth & Performance: Wen Shi 
Senior Vice President, Earned Media: Yun Yu 
Supervisor, Earned Media: Nandi Millet 
Vice President, Influencer: Amanda Roland
Director, Influencer: Kara Cooper  
Executive Vice President, Media & Analytics: Freddy McLaughlin 
Project Management: Stephanie Viall & Christine Pond 
 
Production Co: RSA Films
Director: Marie Schuller
President/Executive Producer: Luke Ricci
Executive Producer: Jenni Sprunger
Director of Photography: Benoit Delhomme
Head of Production: Sarah Morrison
Producer: Emma Cairns
Hair Stylist: Dimitris Giannetos
MUA: Claudine Blythman
Stylist: Mónica Zafra
Production Designer: Jon Blud
Production Manager: Elspeth Vince
Associate Producer: Natalie Orsi 
Production Service Company: Camino
Executive Producer: Laura Díez 
 Editorial: Church @church_edit
Editor: Aaron Saiki  @aaronysaiki
Cutting Assistant: Logan Tarter @logan.tarter
Church Edit Founder: Mah Ferraz @mahferraz
EP NY: Freya Hewett @fruhewett
EP LA/HoP: Elyse Robinson @elyserobinson
Post Producer: Kylie DeVries  @kyliemaedev


Color House: Ethos Studio @ethos_studio
Colorist: Ryan Urzi @ryanurzi
Color Producer: Miraida Gutierrez-Colón @miraidagc
Sr. Color Assist: Will Reininga @willreininga_ 
HOP: Sasha Pace @sashapace 
EP/MD: Eliana Carranza-Pitcher @visualmagic
Founder/EP: James Drew @semajwerd
 
Post: Impossible Objects @_impossibleobjects
VFX Supervisor: Morgan McDermott
VFX Producer: Kim Bifulco
Lead Conform Flame Artist: Mike Roy
Senior Flame Artist: Laychin Lee


Music & Sound: Box of ToysBen Laver
Chris Didlick

Tags: agencyBrandscampaignCindy CrawfordpartnershipUpneeq®
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