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Bastion and Cancer Institute NSW develop ‘Mutations’ Campaign Graphically  Depicting the Hidden Damage of Smoking 

Roastbrief by Roastbrief
March 18, 2026
in Agency, Brands, Campaign
Reading Time: 3 mins read
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Bastion and Cancer Institute NSW develop ‘Mutations’ Campaign Graphically  Depicting the Hidden Damage of Smoking 
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Bastion has partnered with Cancer Institute NSW to develop ‘Mutations’, a powerful new anti-tobacco  campaign designed to confront smokers with the hidden damage caused by every cigarette. 

Delivering an impressive rollout for the Mutations campaign across TV, digital, social and out-of-home, the  launch includes a first-ever train station takeover for the organisation, with commuters at Sydney’s Central  Station encountering graphic representations of the mutations created by smoking as they walk up the  stairs, accompanied by the message: “Every cigarette is a step closer to cancer.” 

The campaign film visualises the hidden harm caused by smoking through a confronting visual idea. As a  smoker lights a cigarette, a disturbing mutation begins to grow on the cigarette itself, representing damage  happening inside the body. The film closes with the question: “If you could see the damage, would you  stop?” leaving viewers with a confronting reflection. 

At Parramatta Station, pillars will be transformed into cigarettes with mutations, designed to stop  commuters in their tracks. 

A second campaign burst will launch in April, featuring a tram takeover and large format cinemagraph out of-home alongside TV, social and digital activity. 

Addison Gazal, Group Strategy Director at Bastion, said the campaign was designed to make the health  risks of smoking feel immediate and personal. 

“One of the barriers to behaviour change is that people who smoke don’t feel the health risk personally.  Mutations was designed to communicate the damage in a new and highly visceral way that people can’t  easily rationalise away or self-exclude from, turning every cigarette into a powerful prompt and reminder of  what smoking is really doing inside their body.” 

Developed in partnership with Cancer Institute NSW, Bastion combined the scale and capability of a global  network with the agility of an independent to deliver an integrated campaign that places the organisation in  a position of strength to reach communities across New South Wales. 

Bastion partnered with Cancer Institute NSW to recreate the successful UK campaign ‘Mutations’ for the Australian market to help combat the increasing number of young people smoking in NSW. With approval from the UK Department of Health and Social Care to adapt ‘Mutations’, the Australian version extends the campaign including with immersive station dominations, using unmissable contextual placements and graphic computer-generated imagery to highlight how smoking causes cell mutations that can lead to cancer. The campaign’s television commercial was filmed in NSW, using local actors to ensure the campaign resonated with an Australian audience

The Mutations campaign is live across TV, digital, social and out-of-home.

Tags: ‘Mutations’agencyBastionBrandscampaignCancer Institute NSWDamage of Smoking
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